And so it begins...

On the flight to Cancun, there's a screaming infant on the plane. We're landing at Cancun, and this fetus is screaming its head off. You wouldn't think a child could make that much noise.

Finally, we land, and then we catch a shuttle to our rental car place, Carribbean Car Rental which is just a scam. There is no such thing as "Caribbean Car Rental" Just a racket. You go to American Car Rental, they put you on a shuttle, and then you go to the American Car Rental and, anything you had reserved from Carribbean Car Rental isn't there. Like, we had a reservation for a Jeep. But they don't have any Jeeps, or so they say. Our shuttle driver points out all of the Jeeps to us as we leave. What a fucking scam.

The shuttle driver drops us off at a cab driver. The cab driver agrees to take us to our hotel in Cancun. On the way, he needs to stop for gas. Jen and I run into the gas station, leaving all of our things in the cab. I take a photo of her and the taxi before we go into the store.

In the store, we start buying armloads of candy, always experimenting with new flavors.

Then, we get back in the van and when we get to the Aloft Cancun hotel, Jen realizes that she can't find the GoPro. It's lost. Not sure where it is. Now, she's upset. We get the taxi driver's phone number. He gets my phone number. And then we check into the hotel.

Shorly thereafter, he's on his way back to the hotel with a camera. We're hoping it's the GoPro. Sure enough. Dude returns to the hotel with the GoPro camera that she left in the shuttle van.

And, these are the people that Americans think you should fear. Half the world is afriad to come down here, and they're the nicest people in the world..

In the morning, we stay at the Aloft Cancun hotel. We are scheduled to check into the Ocean Dream hotel, but check in isn't until 3:00 p.m., and the flight lands at 5:00 a.m. So, my concern was that we'd be sort of stuck with no place to go from 5:00 a.m. - 3:00 p.m., so I made a separate reservation for the same day (essentially) at Aloft Cancun Hotel.

This turned out to be a solid move.

We were both exhausted when we landed, and the Carribbean Rental Car agency is just an internet scam, really. So, we didn't have a car, and we wouldn't really have had a place to go without our reservation for the Aloft Cancun hotel.

On the plane flight down, my glasses somehow broke. And then, walking around cancun, my flipflops tore/failed. So, we bought some new flip flops for me. They get you on the exchange rate down here. Like, the exchange rate is 19 to 1, but they claim it's 15:1, 17:1, 17.5:1, etc.

So, we check in at Aloft Cancun hotel at 6:44 a.m. They let us into the hotel and we crash hard. We both get into bed and promptly fall asleep until noon. Now, they want us out of the hotel, and we're begging for more time. But finally, they tell us "look...you can leave your suitcases in the lobby, and we'll give you towels to go to the beach, but you've got to leave the room. It's 12:45 p.m. and checkout was at noon.

So, we go walk down to the beach on the Carribbean side of the island. Then, we go into the ocean for a swim. The water is the perfect temperature, and we splash about int he waves crashing on us. The water is an amazing aqua color. There are no jellyfish. No stingrays. Nothing like that. It's paradise.

And we swim in the ocean until about 3:00 p.m. Now, we can check in at our other hotel, the Ocean Dream. So, we return the towels, fetch our suitcases, at catch a taxi to the next hotel, the Ocean Dream.

Like, words can't describe now nice the Ocean Dream is. It's not a hotel really. It's condos. So, we have a condo, on the first floor, facing the ocean, overlooking the pool. It's insanely decadent. Not bad considering that I just rolled the dice and picked this place out of a hat. We're litterally poolside. We open our sliding glass doors, and we're at the pool. Amazing.

We swim for a long time in the surt. Then, we walk into town for dinner. We settle on Carlos and Charlies, a famous, insane tourist trap restaurant. It's really indescribable. They're going around, putting balloon animals on people's heads, playing loud music, dancing, blowing whistles, serving shots, and somehow, in the middle of all of this, they're also running a restaurant of sorts. They bring me a yard of mango margarita and Jen gets a tropical dream. Like, this place would be shot down in 2 minutes in the USA.

Then, we walk back and

Categories:

Posted by Rob Kiser on March 26, 2017 at 6:49 AM : Comments (0) | Permalink

DEN - CUN


Cancun

Cancun Sun 3/26- Sun 4/2

Cheapoair Booking: 40284169

United DC55X5 Flight 1971
Depart DEN Sat 3/25/2017 11:59 PM arrive CUN Sun 3/26/2017 4:55 AM

Pick up luggage.
Go outside Terminal 3 to restaurant Margaritaville
Contact our representative he is wearing a red T-shirt.that says America Car Rental.
(They provide the service to Caribbean Rent A Car).
They will take me to the office. And I pick up the car.
I need Credit card..My ID. Drivers license.

Caribbean Rent A Car
01-800-212-0752

Reservation CUN-30191


Check in 3:00 p.m Sunday March 26th

Ocean Dream BPR
Boulevard Kukulcán km 9
Zona Hotelera
Cancun
77500
MX

Check in 3:00 p.m.
Hotels.com conf 136513249350

Check out Monday march 27th 12:00 noon

Monday - Drive to Chichen Itza. Spend the night there.
Hotels.com Confirmation number: 136514959118
Mayaland Hotel And Bungalows
Km 120 Ctra Merida, Zona Arqueologica, In the heart of Chichen Itza, Piste, YUC, 97751, Mexico, 866-209-9122
Check in 3:00 p.m. Monday March 27th
Check out 12:00 noon Tuesday March 28th

Drive to Tulum
Hotel Cabanas Los Lirios Tulum
Hotels.com Confirmation number: 136514711764
Check in Tuesday March 28th
Check out Sun Apr 2
Carretera Tulum Boca Paila S/n Km. 7.5
Zona Hotelera de Tulum
Tulum
77780
MX
+529988879602


Sun, Apr 02, 2017
United 1691

Depart CUN - 02:00 pm
Arrive DEN - 05:20 pm

Categories:

Posted by Rob Kiser on March 23, 2017 at 8:16 AM : Comments (0) | Permalink

Lane-splitting at 110 mph on CA State Highway 60

There's a wildfire a mile from my house burning out of control and I'm heading for the airport. I'm westbound on CA State Highway 60 lanesplitting at 110 mph. I'm not sure what I'll do when I get there, but I need to get there before the fire does. That's for sure. I've got to save the cats. Grab the safe from the flames. We've got to get the guns. Anything of value, and then flee from the fire.

THat's the plan anyway. So, at lunch, I started getting messages about a wildfire near the house and I'm like....messaging people back and forth. Trying to get a handle on the fire. Which way is it going? Is it getting bigger or smaller? Is 285 open Northbound or Southbound?

Like...everyone is sort of trying to get their arms around the situation. What's going on here? How bad is it, really?

I can tell you this...it's close to my house than any other fire has ever been outside of campfires and bbq pits.

So, I'm freaking out. I book a ticket to Denver that departs Ontario at 4:15 pm and I leave the house in Riverside at 3:15 p.m.

Now, I'm folloiwng the GPS but it's going to be close. They should be boarding for my flight as soon as I get to the airport. (3:45 p.m.). So, I'm screaming down highway 60. Like, if there's a cop, then I'm going to jail. It's just that simple. And if people are changing lanes while I'm lane-splitting, then I'm going to die. That's just the way it is.

So I'm screaming down highway 60, but I should mention what I was doing right before I left...before I knew that there was a forest fire about to burn down my house.

So I'm screaming down highway 60 and now, on the way, I start planning where I'll park. I'll park in short term parking right across from the SouthWest terminal. I've seen other people do it. No more long term parking. Now, it's short term parking. And I'm going to be gone for 11 days. Sure, that won't look suspicious, right?

So, I park the KTM in short term parking and get off my bike and as I do, I get a text. Flight is delayed 30 minutes. So, I'll ahve time to get my preboard pass and I'll be first to board afterall. Things are looking up.

Categories:

Posted by Rob Kiser on March 22, 2017 at 5:16 PM : Comments (0) | Permalink

Garmin Montana 600 & Garmin Map Updater on a MacBook Air

http://apple.stackexchange.com/questions/128127/where-are-my-all-installed-programs

All software in Mac OS X is installed in /Applications, which can be found in the Finder sidebar

Most Mac applications don't have to be installed, you just have to copy the applications in the Applications folder. Normally, all installed applications that are in the /Applications folder appear automatically in the Launchpad.

So, I'm not clear why, but my Garmin Express App didn't show up in my Launchpad.

But I do see it in /Applications.

Now, it says "Garmin express does not support this device. Please use Garmin Map Updater."

So, I click Download.

Then, I install it and then I have to install the Garmin Communicator Plugin.

You have Communicator Plugin.
Up to Date, Version 4.2.0.0

Devices Detected
Montana 600 (Unit ID 3882856730)

So, Garmin Express is not what I need. It does not support the Garmin Montana 600.

I did eventually launch the Garmin Map Updater. It looks like I can buy maps of Mexico for about $50 USD ($1,000 Mexican Pesos). But, I want to verify that I can store both countries in the Garmin Montana at the same time. I also want to copy my tracks off of the Garmin montana first.

1) Copy tracks off of Garmin Montana 600.
2) Install maps of Mexico.

OK. So, I think I've discovered before that the EasyGPS software that runs under windows (not Mac) copies the tracks off of the Garmin Montana. Hmmmm.

OK. So, it looks like Apple has some software called Basecamp that is compatible with the Garmin Montana 600.

But, having said that, I think I'm going to try to copy my tracks off using EasyGPS as I already have it installed on a windows machine.

OK. Hook up my Garmin Montana 600 to a laptop running EasyGPS.

Click on GPS - Receive from GPS - Then select Routes, Tracks, & Saved Tracks from Garmin Montana 600. Click OK.

It looks like my tracks go back to July 19, 2016.

So, in the end, I saved these off as s:\garmin\2017_California.gpx.

Now, to upload them onto a map.

Go to http://www.gpsvisualizer.com/

Select your .gpx file.

Click Map It.

So, here is a map of my trips from Los Angeles to SF (and back), and also my trip from Los Angeles to Bahia De Los Angeles and back. (It says it's available temporarily, anyway.)

Now, I'm deleting my tracks so I can start over in Mexico.
----------------------------------------------------------------------
Deleting Tracks from the Garmin Montana 600.
----------------------------------------------------------------------

Tap on Up arrow at bottom center of screen on Garmin Montana 600.
Tap on Track Manager.
Tap on Current Track.
Tap Clear Current Track.
> Do you really want to clear the track log and reset associated trip data?
Tap on Clear.

Tap on Archived Tracks.
Select the top track.
Tap on Delete.
Tap on Delete again.
Rinse. Repeat.

So, it looks like I've successfully erased all of my tracks from my GPS. Lord.

Now, I'd like to install the maps for Mexico on my Garmin Montana 600.

I very nearly had this working on the MacBook Air.
Let's switch back over there and see how that works.

I go to Finder - Favorites - Downloads, I do see GarminMapUpdater.dmg.
So, I click on that. Now, I see Garmin Map Update.
I double click that.
Garmin Map Update is an application downloaded from the internet (horrors). Are you sure you want to open it?

Click Open.

Checking for software updates for Garmin Map Update
Downloading software updates for Garmin Map Update
Welcome to Garmin Map Update. This application will guide you through the map installation process.
Plug in your Garmin GPS device and click on Continue.

Eventually, the shitty software recognizes my gps after I remove and reinstall the cable.

Select the Garmin GPS device you would like to update:
Montana 600 (Unit ID 3882856730).
Click on the only one listed, obviously.
Click Continue.
It's really slow, or buggy, or both. I do it a couple of times. Finally, I get
a license agreement. Check.
To improve future generations, I'll let the NSA stalk me...uncheck.
Continue.
Then, I accidentally clicked twice and it went haywire on me. Let's start over...

OK. Now...A new map update is available for purchase (surprise, surprise).
What would you like to do?
Visit garmin.com to view and purchase available maps.
Click Continue.
It launcches Safari and now at my.garmin.com. Montana 600. Purchasable updates.

FInally, I realize...I already have the maps for Mexico in the stupid thing. Lord God.

Now, I tell it to navigate to my hotel:


Cancun, Quintana Roo, Mexico
.





Categories:

Posted by Rob Kiser on March 22, 2017 at 11:28 AM : Comments (0) | Permalink

Countdown to Spring Break 2017 - Tulum, Mexico

So, Jen and I are trying to get ready for a Spring Break trip to Tulum, Mexico. I'm making lists and mental notes on what we need to buy and what we need to do to be ready for our trip.

Right now, I'm working on copying all of the files off of my cameras onto my MacBook Air. Like, heaven forbid I go on Spring Break and not be able to take any photos, right?

I shot some this morning flying over Mt Evans, Breckenridge, and Copper Mountain.

Now, I'm thinking I have to get these photos off of my cameras onto my MacBook Air, then off of the MacBook Air onto the external 1 TB Seagate drive.

So, I copied all of my photos off of my Canon EOS 50D. Now, format the memory card.

Now copying the photos off of my other Canon EOS 50D. Now formatting the other memory card....


Categories:

Posted by Rob Kiser on March 20, 2017 at 9:38 PM : Comments (0) | Permalink

Alzheimer's Trial

https://clinicaltrials.gov/ct2/show/NCT01409915?term=alzheimers&recr=Open&rank=8

Study of the Safety & Efficacy of Leukine® in the Treatment of Alzheimer's Disease
This study is currently recruiting participants. (see Contacts and Locations)
Verified January 2017 by University of Colorado, Denver
Sponsor:
University of Colorado, Denver
Collaborator:
The Dana Foundation
Information provided by (Responsible Party):
University of Colorado, Denver
ClinicalTrials.gov Identifier:
NCT01409915
First received: August 2, 2011
Last updated: January 24, 2017
Last verified: January 2017
History of Changes
Full Text View Tabular ViewNo Study Results PostedDisclaimerHow to Read a Study Record
Purpose
A medicine that is FDA-approved for bone marrow stimulation (called Leukine) will be tested for its ability to be tolerated by Alzheimer's disease patients and potentially to improve their memory.

Condition Intervention Phase
Alzheimer's Disease
Drug: Sagramostim
Drug: Saline -- placebo comparator
Phase 2

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Participant, Care Provider, Investigator
Primary Purpose: Treatment
Official Title: Pilot Phase 2 Trial of the Safety & Efficacy of Granulocyte-Macrophage Colony-Stimulating Factor (Leukine®) in the Treatment of Alzheimer's Disease

Resource links provided by NLM:

Genetics Home Reference related topics: Alzheimer disease
MedlinePlus related topics: Alzheimer's Disease
Drug Information available for: Sargramostim
Genetic and Rare Diseases Information Center resources: Familial Alzheimer Disease
U.S. FDA Resources

Further study details as provided by University of Colorado, Denver:

Primary Outcome Measures:
Ability of Alzheimer's Disease subjects to tolerate Leukine treatment will be assessed [ Time Frame: Up to 5 months ]
Various tests of well being and toxicity will be monitored for 3 months after treatment


Secondary Outcome Measures:
Ability of Leukine treatment to improve cognition of Alzheimer's Disease subjects [ Time Frame: Up to 5 months ]
Neuropsychological measures will be assessed at various intervals up to 3 months following treatment (or placebo)


Estimated Enrollment: 40
Study Start Date: March 2011
Estimated Study Completion Date: December 2017
Estimated Primary Completion Date: November 2017 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Sagramostim (Leukine)
5 subjects 250 mcg /m2/day Leukine subcutaneously for 5 days/week for three weeks. Data and Safety Monitoring Board will then review data and recommend whether to continue at the same current recommended dose for additional subjects or to reduce the dose by half if excessive leukocytosis occurs
Drug: Sagramostim
5 subjects 250 mcg /m2/day Leukine subcutaneously for 5 days/week for three weeks. Data and Safety Monitoring Board will then review data and recommend whether to continue at the same current recommended dose for additional subjects or to reduce the dose by half if excessive leukocytosis occurs
Other Names:
Leukine
Granulocyte-Macrophage Colony-Stimulating Factor
Placebo Comparator: Control Group
Saline -- placebo comparator. Given as a subcutaneous injection.
Drug: Saline -- placebo comparator
subcutaneous injection
Other Name: Sterile solution of sodium chloride in water

Detailed Description:
Preliminary preclinical results demonstrated that GM-CSF (Granulocyte macrophage colony-stimulating factor, e.g. Leukine®/Sargramostim) rapidly reduced cerebral amyloid deposition and completely reversed memory deficits in transgenic mouse models of Alzheimer's Disease (AD). To assess the efficacy of GM-CSF in humans, the investigators performed a retrospective analysis of a cognition study of human patients undergoing hematopoietic cell transplantation for cancer and who garner cognitive impairments from the chemotherapy or irradiation. In the patients that received a colony-stimulating factor (CSF) to stimulate the bone marrow and recover immune system function, the investigators found that those who received GM-CSF (Leukine®/Sargramostim) plus G-CSF (Filigrastim) significantly improved in cognitive function as compared to those who received G-CSF alone. These findings combined with over two decades of accrued safety data using recombinant human GM-CSF, Leukine®/Sargramostim, in elderly leukopenic patients, suggested that Leukine® should be tested as a treatment to reverse cerebral amyloid pathology and cognitive impairment in AD.
Eligibility

Ages Eligible for Study: 55 Years to 85 Years (Adult, Senior)
Sexes Eligible for Study: All
Accepts Healthy Volunteers: No
Criteria
Inclusion Criteria:

age 55 to 85 years;
should have a mild-to-moderate Alzheimer's Disease diagnosis (Mini-Mental State Examination 10-26 inclusive);
if on anti-dementia treatment should be on stable treatment for at least 2 months (i.e. cholinesterase inhibitor and/or Memantine or Axona);
stable on all other medications for at least 30 days prior to screen;
should be fluent in English;
should be physically able to participate by medical history, clinical exam and tests;
should have a study partner to accompany them to scheduled visits.
Exclusion Criteria:

clinically relevant arrhythmias;
a resting pulse less than 50;
active cancer other than non-melanoma skin cancers;
use of another investigatory drug within 2 months of screening;
significant stroke or head trauma by history or MRI;
contraindication for having a MRI;
diagnostic and Statistical Manual of Mental Disorders-IV criteria for a current major psychiatric disorder;
sensitivity to yeast or yeast products;
impaired kidney function as measured by a Glomerular Filtration Rate less than 60 milliliters/min;
preexisting fluid retention, pulmonary infiltrates, or congestive heart failure;
history of moderate-to-severe lung disease;
history of moderate-to-severe liver disease;
pregnant women, or any women who feel they are likely to become pregnant during the study;
prisoners.
Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01409915

Contacts
Contact: Joseph Daniels, MPH 303-724-2997 Joseph.Daniels@ucdenver.edu
Contact: Helen Gray, MBA 303-724-8965 Helen.Gray@ucdenver.edu

Locations
United States, Colorado
University of Colorado Denver, Anschutz Medical Campus Recruiting
Aurora, Colorado, United States, 80045
Contact: Joseph S Daniels, MPH, ACSM 303-724-2997 joseph.daniels@ucdenver.edu
Principal Investigator: Huntington Potter, PhD
Sub-Investigator: Jonathan Woodcock, MD
Sponsors and Collaborators
University of Colorado, Denver
The Dana Foundation
Investigators
Principal Investigator: Huntington Potter, PhD University of Colorado, Denver
More Information

Responsible Party: University of Colorado, Denver
ClinicalTrials.gov Identifier: NCT01409915 History of Changes
Other Study ID Numbers: 12-1273
Study First Received: August 2, 2011
Last Updated: January 24, 2017

Keywords provided by University of Colorado, Denver:
Alzheimer's disease
neuropsychological assessment
Granulocyte-Macrophage Colony-Stimulating Factor
Leukine

Additional relevant MeSH terms:
Alzheimer Disease
Dementia
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Tauopathies
Neurodegenerative Diseases
Neurocognitive Disorders
Mental Disorders

ClinicalTrials.gov processed this record on March 16, 2017

Categories:

Posted by Rob Kiser on March 16, 2017 at 9:53 PM : Comments (0) | Permalink